Event

The development of therapeutic approaches to treat lung disease requires an understanding of both the normal and disease physiology of the lung. Although traditional experimental approaches address either organ or cellular physiology, the use of lung slice preparations provides a unique approach to investigate integrated physiology that links the cellular and organ responses. Moreover, living lung slices are robust, can be prepared from a variety of species, including humans, and retain many aspects of the cellular and structural organization of the lung. This seminar will describe methods to prepare, store, and utilize lung slices as a tool to investigate lung diseases.