Event

This is a new session in the very successful series of ATS Mythbusters, in which leading researchers give talks relevant to a controversial hypothesis, after which expert “mythbusters” discuss its validity, and audience members ultimately vote on whether the myth has been accepted or busted. In this provocative session, the hypothesis to be examined is that as we learn more about fibrogenesis, a common prime mover will emerge as the driving force in most cases of pulmonary fibrosis. Speakers will present evidence supporting the proposition that abnormalities in the "OMICS" or "OMES" that they discuss are driving the abnormal tissue injury and repair seen in fibrotic lung disease, especially IPF. The candidate OMEs proposed to be the main culprit in fibrosis will be the transcriptome, the genome, the proteome, the microbiome or the metabolome. The session will debate whether abnormalities in one of these OMEs “rules them all” in pulmonary fibrosis.