The session will review the impact of three controversial intensive care unit therapies (intravenous fluids, neuromuscular blockade and early mobilization) on patient centered outcomes. The session will follow a pro-con format led by experts in these three therapies. Speakers will review the pertinent literature in support of their position and identify research gaps in our knowledge of long-term effects of ICU therapies. After the pro and con positions are presented, there will be discussion time allotted for debate between the speakers and with the audience members.