This comprehensive course will provide the learner with a strategy to care for critically ill patients with various diseases of the pulmonary vasculature and right ventricle. Presenters will provide a framework for understanding pathophysiology, hemodynamics, and specific high-risk scenarios using state of the art evidence and clinical expertise. Common pitfalls and knowledge gaps in caring for patients with pulmonary vascular and right heart failure will be addressed. By the session’s conclusion, learners should have a refined approach for the management of these challenging patients.